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Triple Combination Creams

TCCs are the most effective topical treatments for skin pigmentation.


Steroid + tyrosinase inhibitor + retinoid.


TCC remains the gold standard skin treatment for pigmentation and can take 12-16 weeks to work.


The first used contained a combination of 0.1% tretinoin, 5% hydroquinone (HQ) and 0.1% dexamethasone (a steroid). 


These all act together to eliminate each other's side effects. TCC can be usefully combined with cleansers and moisturisers.


Apply over the moisturiser.


Use every third night initially for two weeks, then every two days for two weeks.


Then nightly.


The only FDA-approved TCC on the market is Triluma.

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