top of page

Retinoids

Retinoids are the quintessential first-line treatment for acne vulgaris

Retinoids

Retinoids reduce keratinocyte proliferation by binding to specific receptors in the cell's nucleus. Retinoids also reduce skin bacteria by reducing their supply of nutrients.



Retinoid Generations


Currently, there are four FDA-approved generations of topical retinoids:


First Generation


Tretinoin, also referred to as all-trans retinoic acid (ATRA)


Second Generation


Acitretin

Etretinate


Third Generation


Adapalene and tazarotene


Fourth Generation


Trifarotene - fourth-generation.



Side effects with Retinoids


The most common adverse effects of topical retinoid use are drying, stinging, and burning upon application.



Combining Retinoids


Retinoids have recently been combined with BPO as a combined treatment.

bottom of page